STYLAGE® L BI-FLEX®

Description

Name: STYLAGE® L BI-FLEX®
Manufacturer: Vivacy
Active Substance(s): CROSS-LINKED HYALURONIC ACID (HA), MANNITOL
Strength: 24mg/g HA, 9mg/ml Mannitol
Package Content: 2 x 1ml Pre-Filled Syringes, 4 x 30G ½ Needles

STYLAGE® L BI-FLEX® is a versatile injectable hyaluronic acid filler developed by Laboratories VIVACY, France, for licensed aesthetic professionals managing deep wrinkle correction and facial volume loss. Formulated with 24mg/g cross-linked hyaluronic acid and 9mg/mL mannitol, this STYLAGE® dermal filler uses IPN-Like Technology™ and the BI-FLEX® rheological profile to support smooth injection and durable correction across multiple treatment areas. Supplied as 2 × 1mL prefilled syringes, the formulation contains no lidocaine, allowing practitioners greater flexibility in anesthesia management. Practitioners seeking to buy STYLAGE® L BI-FLEX® online may contact Maylips support team for guidance.

• Strength: 24mg/g HA | 9mg/mL Mannitol
• Active Ingredient: Hyaluronic acid (cross-linked) 24mg/g; Mannitol 9mg/mL
• Dosage Form: Injectable gel — 2 × 1mL prefilled syringes + 4 × 30G ½ needles
• FDA Approval: STYLAGE® is NOT FDA-approved. The product carries CE marking for European Union markets only. Practitioners in the U.S. should be aware that STYLAGE® products are not legally marketed for clinical use in the United States.
• Molecular Type: Cross-linked hyaluronic acid (IPN-Like Technology™)
• Intended Use: Deep wrinkle correction, volume restoration, versatile facial contouring — for licensed aesthetic professionals
• Brand: STYLAGE®
• Country of Origin: France
• Manufacturer: Laboratories VIVACY (Paris, France)

STYLAGE® L BI-FLEX® differs from many standard hyaluronic acid fillers because it combines IPN-Like Technology™, mannitol, and a versatile rheological profile in a formulation designed for multiple treatment areas and injection depths. Utilizing the updated BI-FLEX® system, which replaces older Bi-SOFT® syringe designs with improved ergonomics and lower injection force, the product is recognized among aesthetic medicine professionals for its adaptability across wrinkle correction, facial contouring, and volume restoration procedures.

A defining feature of the STYLAGE® filler range is IPN-Like Technology™, which uses two interlocked hyaluronic acid polymer networks to improve cohesivity, elasticity, and resistance to deformation compared with conventional fillers. This structure helps maintain gel integrity while supporting smoother tissue integration and natural-looking correction outcomes. The inclusion of mannitol further distinguishes the formulation, as it acts as a free radical scavenger that may reduce oxidative degradation and extend product durability.

Many practitioners evaluating whether STYLAGE® is a good filler highlight its longevity, BI-FLEX® versatility, and no-lidocaine formulation, which allows customized anesthesia protocols. STYLAGE® products are CE-marked for use in the EU, but practitioners should independently verify the current regulatory status in the United States and other jurisdictions before use or procurement.

STYLAGE® L BI-FLEX® is indicated for deep wrinkle correction, facial contouring, and moderate volume restoration in adult patients treated by licensed medical professionals. Common treatment areas include:

• Nasolabial folds
• Marionette lines
• Perioral rhytids and glabellar lines
• Cheek and midface volumization
• Chin and jawline contouring

The STYLAGE® L BI-FLEX® injection is typically administered into the mid-to-deep dermis or the subcutaneous plane, depending on the treatment area, severity of volume loss, and desired correction. Because BI-soft is considered a versatile dermal filler, its rheological profile adapts well to varied injection planes and anatomical regions.

Patient selection should take into account the condition of the patient’s skin, tissue laxity, previous filler treatments, and factors such as skin type and metabolic activity. Patients with active infection, inflammation, or known hypersensitivity to hyaluronic acid products should be appropriately assessed before treatment. STYLAGE® L BI-FLEX® is intended exclusively for trained aesthetic medicine professionals; self-administration is contraindicated.

STYLAGE® L BI-FLEX® works through cross-linked hyaluronic acid that binds and retains water molecules within dermal tissues, producing immediate volumizing and wrinkle-filling effects following injection. IPN-Like Technology™ creates an interpenetrating network of hyaluronic acid polymers that improves cohesivity and resistance to mechanical deformation, helping maintain gel integrity over time while supporting natural tissue movement in dynamic facial regions.

Mannitol provides additional stability by scavenging free radicals that promote oxidative degradation of hyaluronic acid, potentially prolonging filler longevity compared with standard formulations lacking antioxidant support. Because STYLAGE® L BI-FLEX® contains no integrated anesthetic, practitioners manage anesthesia separately according to procedural preference and patient tolerance. STYLAGE® L BI-FLEX® remains fully reversible through hyaluronidase administration if correction adjustment or emergency dissolution is required.

STYLAGE® L BI-FLEX® injections must only be administered by qualified medical professionals experienced in facial anatomy and injectable procedures.

Injection Techniques & Placement

• Recommended Depth: Inject into the mid-to-deep dermis or subcutaneous plane, depending on the specific treatment area and the severity of volume loss.
• Common Techniques: Linear threading, fanning, and cross-hatching.
• Anesthesia Management: Because this formulation contains no co-formulated anesthetic, topical or local anesthesia should be applied separately prior to treatment, where appropriate.

Post-Treatment Care

Following the injection, advise patients to avoid the following until local swelling and redness completely subside:

• Excessive sun or UV exposure
• Saunas and steam rooms
• Strenuous physical activity

Common Side Effects

The following localized reactions are generally transient, mild, and self-limiting. Recovery time varies based on skin type, treatment area, and injection depth:

• Redness and swelling
• Tenderness and mild discomfort
• Bruising at the injection site (typically resolves within a few days)
• Temporary firmness in the treated area

Serious Adverse Events

While rare, serious complications can occur with all hyaluronic acid fillers. Practitioners must maintain familiarity with emergency management protocols and the immediate use of hyaluronidase. Potential risks include:

• Vascular occlusion
• Skin necrosis
• Localized infection
• Delayed inflammatory nodules
• Visual disturbances

Screen all patients for hyaluronic acid hypersensitivity and other standard contraindications prior to treatment. Always consult the full Instructions for Use (IFU) for comprehensive safety guidance.

STYLAGE® L BI-FLEX® is manufactured in France by Laboratories VIVACY and is CE-marked for professional aesthetic use within applicable European markets. Current FDA approval status and regional regulatory requirements should be independently verified before procurement or clinical use in the United States or other jurisdictions. Practitioners who wish to buy dermal fillers or buy STYLAGE® may contact Maylips support team for sourcing information and documentation support.

For sourcing guidance, contact Maylips support team.

Regulatory information current as of mid 2026. Practitioners should confirm local regulatory status before sourcing.