HCG 12000iu

Description

Strength: 12000iu
CAS: 9002-61-3
Chemical Formula: C₁₁₀₅H₁₇₇₀N₃₁₈O₃₃₆S₂₆
Molecular weight: ~36.7 kDa (37,000 Da)
Synonyms: Human Chorionic Gonadotropin, Chorionic gonadotropin, Choriogonin, Endocrine, Gonabion
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.

Human Chorionic Gonadotropin (HCG) is a naturally occurring glycoprotein hormone widely studied for its role in reproductive and endocrine signaling. Structurally and functionally similar to luteinizing hormone (LH), HCG provides prolonged LH/CG receptor stimulation due to its extended biological half-life. The 12,000 IU format is commonly used in research and clinical investigations focused on fertility, gonadal function, and hormone regulation.

HCG is supplied as a lyophilized (freeze-dried) powder to preserve molecular integrity and biological activity prior to reconstitution. Laboratories and qualified providers that buy HCG peptides typically use this format in regulated medical or investigational settings.

• LH-Mimicking Activity: Functions as a long-acting LH analog, enabling sustained receptor activation
• High-Concentration Format: 12,000 IU vial supports extended studies or multiple protocol preparations
• Reproductive Research Utility: Used in investigations involving ovulation, spermatogenesis, and gonadal signaling
• Complex Glycoprotein Structure: Glycosylation enhances receptor binding, stability, and circulation time
• Lyophilized Stability: Freeze-dried formulation supports storage integrity and controlled reconstitution

HCG exerts its biological activity by binding to LH/CG receptors expressed in ovarian and testicular tissue, activating intracellular signaling pathways involved in steroidogenesis and gametogenesis. Its beta subunit confers hormonal specificity, while glycosylation delays metabolic clearance, resulting in prolonged activity compared with endogenous LH.

Researchers who order HCG peptides study these mechanisms in:

• Female reproductive research: Ovulation induction protocols in assisted reproduction models
• Male endocrine studies: Stimulation of endogenous testosterone production and testicular signaling
• HPG axis maintenance: Sustained hypothalamic–pituitary–gonadal signaling in controlled systems
• Hormone suppression models: Gonadal response during or following testosterone suppression

All applications are confined to approved medical or research contexts.

Research and clinical dosing vary by indication and study design. High-strength vials, such as 12,000 IU, allow flexible dilution and multi-dose preparation. As for the observed effects, studies consistently demonstrate ovulation induction in women and testosterone stimulation in men with hypogonadotropic conditions

Investigations into metabolic or weight-related effects exist; however, regulatory authorities discourage off-label use for weight loss due to insufficient supporting evidence

Proper storage and handling are essential to preserve potency, stability, and dosing accuracy, particularly for those who buy HCG peptides for regulated use.

• Storage (lyophilized): Stable at room temperature until expiration; protect from heat, moisture, and light
• Post-reconstitution: Store at 2–8°C; typical stability ranges 30–60 days, depending on formulation
• Handling: Do not freeze reconstituted solutions; minimize light exposure and use amber vials when possible
• Reconstitution: Gently swirl to dissolve; do not shake. Dilute carefully to maintain accuracy with high-IU formats

References

https://academic.oup.com/edrv/article/39/5/549/5036715
https://pmc.ncbi.nlm.nih.gov/articles/PMC5217336/

https://pmc.ncbi.nlm.nih.gov/articles/PMC7381339/

https://pmc.ncbi.nlm.nih.gov/articles/PMC8851198/

https://academic.oup.com/biolreprod/article/68/2/448/2683460

Compliance Notice

This product is intended for laboratory research use only and is not approved for human or veterinary use.