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ID: 25138
Categories: Muscle Growth & Performance Peptides, Peptides for Research
GHRP-2 5mg
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Brand: NOVERA COMPOUNDS
Strength: 5mg
CAS: 158861-67-7
Chemical Formula: C₄₅H₅₅N₉O₆
Molecular weight: 817.97 g/mol
Peptide Sequence: H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2
Synonyms: GHRP2, Pralmorelin, Growth Hormon Releasing Peptide-2
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.
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Log In / Sign UpGHRP-2 is a synthetic growth hormone–releasing peptide studied for its effects on endocrine signaling. Research suggests that it may stimulate growth hormone secretion and metabolic activity, primarily through activation of ghrelin receptors involved in pituitary hormone release.
Disclaimer : Available as lyophilized (freeze-dried) powder for laboratory and in vitro research applications. Reconstitution solution is not included in the pack.
Purity ≥99%
Made in USA
Research Use Only
Fast Shipping
The Novera Compounds Advantage
Made in the USA
Manufactured in the United States under controlled standards. Reliable production. Dependable supply. No overseas uncertainty.
High Purity — 99% or Better
Every batch meets ≥99% purity specifications and is verified by independent third-party laboratory testing. Clean. Consistent. Documented.
Advanced Lyophilized Stability
Carefully lyophilized for structural integrity and easier handling. No cold shipping required. No dry ice. No complications.
Designed for Research
Ideal for scientific study, analytical testing, and research workflows where consistency and quality matter most.
Smart Pricing. Real Value.
High purity. USA-made. Third-party tested. Priced to make sense.
Everything in One Order
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Product Description
Specifications
Description
Strength: 5mg
CAS: 158861-67-7
Chemical Formula: C₄₅H₅₅N₉O₆
Molecular weight: 817.97 g/mol
Peptide Sequence: H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2
Synonyms: GHRP2, Pralmorelin, Growth Hormon Releasing Peptide-2
Storage: Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.
Shelf life: 24 months from the manufacturing date.
GHRP-2 (5mg) About This Product
GHRP-2 is a synthetic hexapeptide developed for laboratory and preclinical research involving endocrine signaling and metabolic regulation. The GHRP-2 peptide consists of six amino acids and has a molecular weight of approximately 817 Da. Its structure incorporates multiple D-amino acid residues, which enhance conformational stability and resistance to enzymatic degradation in experimental systems.
GHRP-2 has been examined in research settings as a synthetic agonist of the growth hormone secretagogue receptor 1a (GHS-R1a), also known as the ghrelin receptor. Activation of this G protein–coupled receptor (GPCR) initiates Gq/phospholipase C (PLC) signaling and calcium-dependent intracellular cascades that regulate growth hormone secretion, metabolic sensing, and gene-expression responses under controlled conditions.
This product is supplied as a sterile, lyophilized powder with a reported purity of ≥98%, packaged in a sealed research-grade vial. Laboratories that buy GHRP-2 peptide commonly use the 5 mg format to support receptor-level studies, signaling assays, and comparative endocrine research workflows.
GHRP-2 (5mg) Key Features and Benefits
- GHS-R1a (Ghrelin Receptor) Agonist: Enables targeted studies of ghrelin-pathway signaling
- D-Amino Acid Composition: Improves peptide stability in laboratory environments
- High Research Purity (≥98%): Verified by analytical testing
- Lyophilized Formulation: Supports stability, reconstitution accuracy, and storage flexibility
- Short-Chain Hexapeptide: Suitable for receptor pharmacology and structure–activity analyses
GHRP-2 (5mg) Mechanism & Research Applications
GHRP-2 functions as a selective agonist of GHS-R1a, a GPCR expressed in the pituitary gland, hypothalamus, and selected peripheral tissues. Receptor activation triggers PLC-dependent calcium mobilization, downstream kinase signaling, and transcriptional programs associated with growth hormone release and cellular stress response.
In research environments, GHRP-2 is used to investigate receptor activation kinetics, intracellular signaling cascades, and tissue-specific receptor expression.
Primary Research Domains
Receptor Pharmacology
- GHS-R1a binding affinity and activation assays
- Structure–activity and signaling-bias investigations
Muscle Biology
- Protein synthesis and degradation pathways
- Modulation of ubiquitin–proteasome markers (atrogin-1, MuRF1)
Energy Balance & Feeding Regulation
- Hypothalamic nutrient-sensing networks
- Appetite-related behavioral and signaling outcomes
Cardiac Cell Stress Models
- Cardiomyocyte apoptosis and oxidative-stress signaling
- Cellular survival responses in myocardial injury paradigms
Immunology
- Thymic signaling pathways and T-cell maturation
- Immune-cell output and diversity in aging or stress models
Neurobiology
- Sleep–wake regulation and sleep-stage distribution
- Nociceptive processing and opioid-receptor crosstalk
Laboratories that order GHRP-2 peptide often incorporate it into comparative studies alongside other growth hormone secretagogues and ghrelin-pathway ligands.
GHRP-2 (5mg) Dosing & Observed Effects in Research
Published research involving GHRP-2 commonly reports microgram-level dosing, adjusted according to experimental model, route of administration, and study duration. Investigations span cell-culture systems, tissue explants, rodent models, and large-animal preclinical studies.
Reported experimental endpoints include:
- Growth hormone elevation
- Changes in food-intake behavior and appetite signaling
- Modulation of muscle protein-turnover markers (atrogin-1, MuRF1)
- Alterations in cardiomyocyte apoptosis and oxidative-stress indicators
- Shifts in thymic output and immune-cell maturation
- Changes in sleep-stage distribution and nociceptive signaling
All findings derive exclusively from preclinical laboratory and animal research and remain model-specific.
GHRP-2 (5mg) Storage, Safety & References
Store GHRP-2 (5mg) as a lyophilized powder protected from light and moisture.
- Short-term storage: 2–8°C
- Long-term storage: –20°C or lower
Avoid repeated freeze–thaw cycles. Reconstitute using sterile laboratory-grade diluents under aseptic conditions and follow protocol-specific stability requirements.
References
https://pmc.ncbi.nlm.nih.gov/articles/PMC3297037/
https://pubmed.ncbi.nlm.nih.gov/7479958/
https://pmc.ncbi.nlm.nih.gov/articles/PMC4760683/
https://www.pnas.org/doi/10.1073/pnas.1212137110
https://pubmed.ncbi.nlm.nih.gov/19819949/
https://www.jci.org/articles/view/30248
Compliance Notice
This product is intended for laboratory research use only and is not approved for human or veterinary use.
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