BOCOUTURE® 100u (XEOMIN®) 1 vial

Description

Name:BOCOUTURE® 100u (XEOMIN®)
Manufacturer: Merz Pharma
Active Substance(s): BOTULINUM TOXIN TYPE A
Strength: 100u
Pack Size: 100u – 1 vial
Accessories: 1 x 100u Powder Single Use Vial

BOCOUTURE® 100u (XEOMIN®) is a botulinum toxin type A used for both medical and aesthetic treatments. It acts as a neuromuscular blocking agent, inhibiting acetylcholine release to reduce muscle activity. It is indicated for treating upper limb spasticity, cervical dystonia, blepharospasm, and glabellar lines. Unlike other botulinum toxins, BOCOUTURE® is free from complexing proteins, reducing the risk of antibody formation and ensuring consistent efficacy.

Key Features:

• Pure botulinum toxin type A, free from complexing proteins for a lower risk of resistance.
• Long-lasting results, typically lasting up to 3 months, depending on the treatment area.
• Versatile applications, used for both therapeutic and cosmetic indications.

BOCOUTURE® 100u is supplied as a lyophilized powder in a single-use glass vial. The vials come in 50-unit, 100-unit, and 200-unit strengths and require reconstitution before use.

Ingredients:

• IncobotulinumtoxinA (Botulinum Toxin Type A): Blocks nerve signals to targeted muscles.
• Human Albumin (1 mg): Stabilizes the toxin during storage and reconstitution.
• Sucrose (4.7 mg): Serves as a cryoprotectant.

BOCOUTURE® 100u is indicated for both medical and aesthetic applications. It is commonly used to reduce muscle overactivity and improve skin appearance by softening wrinkles and treating neuromuscular disorders.

Indications:

• Medical Uses:
  • Upper limb spasticity in adults, with a maximum dose of 400 units per session.
  • Cervical dystonia, with an initial dose of 120 units per session.
  • Blepharospasm, typically 1.25 to 2.5 units per injection site.
• Aesthetic Uses:
  • Glabellar lines (frown lines): 20 units per session, divided into five injections.

Contraindications:

• Hypersensitivity to botulinum toxin type A or other ingredients.
• Infection at the injection site.
• Pregnant or breastfeeding women, due to insufficient safety data.

Side Effects:

• Common (≥5% of patients): Swelling, bruising, headache, muscle weakness.
• Less Common (1-5% of patients): Dysphagia, dry mouth, eyelid ptosis, injection site pain.

Rare but serious: Difficulty breathing or swallowing, requiring immediate medical attention.

BOCOUTURE® 100u is administered via intramuscular injection, requiring precise dosage and placement for optimal results. The number of injections and units used vary depending on the indication.

Administration Technique:

1. Reconstitute the vial with preservative-free 0.9% sodium chloride injection.
2. Gently mix the solution by swirling; do not shake.
3. Use a fine-gauge needle (e.g., 30G for aesthetic use, 26G for medical use).
4. Inject intramuscularly in the target area, avoiding sensitive structures.
5. Treatment intervals:
   • Upper limb spasticity: Every 12 weeks.
   • Cervical dystonia: Every 12 weeks.
   • Blepharospasm: Every 12 weeks.
   • Glabellar lines: Every 3 months.

Storage Guidelines:

• Store at 2°C to 8°C before reconstitution.
• Use within 24 hours after reconstitution.
• Do not freeze or expose to direct sunlight.

BOCOUTURE® 100u (XEOMIN®) is a highly purified botulinum toxin with a well-established safety profile, ensuring effective and predictable results for both medical and cosmetic applications.